Product Name :
NHE-1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
amiloride-sensitive antibody APNH antibody APNH1 antibody FLJ42224 antibody Na Li countertransporter antibody Na(+)/H(+) antiporter antibody Na(+)/H(+) exchanger 1 antibody Na+ H+ antiporter amiloride-sensitive antibody Na+ H+ antiporter antibody Na+ H+ exchanger 1 antibody 展开
Function :
The sodium-hydrogen antiporter 1 (NHE-1) also known as sodium/hydrogen exchanger 1 or SLC9A1 (SoLute Carrier family 9A1) is an isoform of sodium–hydrogen antiporter that in humans is encoded by the SLC9A1 gene.The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in volume- and pH-regulation of vertebrate cells. It is inhibited by the non-specific diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others.Sodium–hydrogen antiporter 1 has been shown to interact with carbonic anhydrase II and CHP. It is also the target of the experimental drug rimeporide, which is being developed for the treatment of Duchenne muscular dystrophy.88284-48-4 Price
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within mouse NHE-1 aa 36-85 / 820.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069435
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.926280-83-3 Order Aliquot store at -20℃.PMID:33467950 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 91/61 kDa
Positive control :
Rat skin lysates, A431, 293T, LOVO, human kidney tissue, mouse colon tissue, human small intestine tissue.