Product Name :
Phospho-Met (Y1234/Y1235) Recombinant Rabbit Monoclonal Antibody [PSH06-90]
Predicted band size :
156 kDa
Observed band size :
145 kDa
Synonyms:
AUTS9 antibody c met antibody D249 antibody Hepatocyte growth factor receptor antibody HGF receptor antibody HGF/SF receptor antibody HGFR antibody MET antibody Met proto oncogene antibody Met proto oncogene tyrosine kinase antibody 展开
Function :
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. HGF receptor is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its splicing isoform (NK1, NK2) are the only known ligands of the HGF receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF/SF is restricted to cells of mesenchymal origin. When HGF/SF binds its cognate receptor MET it induces its dimerization through a not yet completely understood mechanism leading to its activation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic phospho-peptide corresponding to residues surrounding Tyr1234/Tyr1235 of human Met aa 1,201-1,250.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
PSH06-90
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 362522-50-7 Aliquot store at -20℃.5-Bromopyridine-2-sulfonyl chloride Order Avoid repeated freeze / thaw cycles.PMID:33745409
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 156 kDa
Positive control :
HeLa cell lysate, HeLa starved for 16 hours then treated with 20ng/mL HGF for 10 minutes cell lysate.